8th NACG workshop and symposium in Oslo

An updated invitation with full agenda and practical information about participation is available here.

Deadline for registration: 1 Nov 2019.

After this date, please contact us at post@nordicclinicalgenomics.org.

Symposium:

Welcome and opening remarks

• Dag E. Undlien, Oslo University Hospital, NACG chair

• Kenneth Vareide, CEO Digital Solutions, DNV GL

• Paul Chaffey, State Secretary to the Minister of Digitalisation, Norway

National initiatives

• Key note speaker: Bettina Lundgren, Director of the Danish National Genome Centre

• Anna Lindstrand, Genomic Medicine Sweden / Karolinska Institute

• Aarno Palotie, research director of the Human Genomics program at FIMM, Finland

The European 1+ Million Genomes Initiative from a Norwegian perspective

• Grethe Synnøve Foss, project manager for the Norwegian Strategy for Personalised Medicine at the Directorate for Health and Care

Nordic Per Med Law initiative on the regulatory framework for personalised medicine

• Gjertrud Bøhn Mageli, Oslo University Hospital

Data sharing: Variant Exchange experiences – practical cross-border sharing

• Stephen McAdam, Digital Health Development Director, DNV GL

Next generation sequencing of Common and Rare diseases in Iceland

• Patrick Sulem, Head of Clinical sequencing, deCODE genetics Iceland

Clinical genomics at scale; lessons from Illumina

• Paul Jones, Head of Population Genomics, EMEA, Illumina

Genomic medicine in cancer & clinical trials

• Kristoffer Rohrberg, head of phase I unit, Rigshospitalet, Copenhagen

• Caroline Heckman, Institute for Molecular Medicine Finland (FIMM) / iCAN

• Valtteri Wirta, Facility director, SciLifeLab

Genomic medicine in cancer & clinical trials – precision drugs

• James Hadfield, Director and Principal Diagnostic Scientist, Precision Medicine Laboratories at AstraZeneca

• Duarte Marchand, Country Manager for Takeda

Genomic medicine in cancer & clinical trials

• Panel discussion with speakers from the morning session, moderated by Valtteri Wirta.

Workshops:

• Consent

  • Facilitated by Sharmini Alagaratnam, DNV GL and Kaisa Kettunen, FIMM

  • This 3-hour workshop aims to compare different approaches to consent in clinical genomics, as well as to identify and discuss common challenges and unresolved issues related specifically to the use of NGS in clinical diagnostics.

• Structural variants and Bioinformatic tools development (combined workstreams)

  • Facilitated by Oleg Agafonov, DNV GL, Mads Bak, Rigshospitalet, Tony Håndstad, OUS AMG and Rasmus Lykke Marvig, Rigshospitalet

  • In this session, Nordic laboratories will share their experiences in using SVs for clinical diagnostics. We will first examine SV calling methodology and compare benchmarking results from different laboratories. Then we will go into more detail on downstream processing, including tools and strategies for clustering/merging results of multiple callers, annotation, and frequency counting. Finally, we will discuss how to best visualize SVs and interpret them.

• NGS for cancer diagnostics

  • Facilitated by Vibeke Binz Vallevik and Courtney Nadeau, DNV GL

  • This session will examine topics related to the patient pathways, guidelines, and technical pipelines for somatic sequencing in the Nordics. Preliminary data from the BigMed project, which has mapped molecular diagnostics supporting cancer treatment at several Nordic hospitals, will be presented. The goal of this workshop is to share an overview of routine somatic sequencing in the different countries and to identify important topics to address through the NACG forum.

• MDR and IVDR - how to address the upcoming regulations?

  • Alex Shiryaev, DNV GL Presafe AS

  • All actors involved with medical devices, from their manufacture to their use, will have to comply with the new regulations by May 2020 (May 2022 for in vitro diagnostic medical devices). This session will provide an introduction to the European regulations on Medical Devices (MDR) and In Vitro Diagnostics Medical Devices (IVDR), followed by a discussion on applicability to hospital (lab) developed tests (LDTs) and preparations for the transition.

Nordic conference: The legal framework for personalised medicine

Adjacent to the NACG event (18.-19. Nov 2019) there will be a conference on The legal framework for personalised medicine (Rettslige reguleringer av persontilpasset medisin) organized at the same venue. For more information please visit the external event website. Deadline for registration: 25. Oct 2019

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